{"id":4934,"date":"2025-11-16T14:17:52","date_gmt":"2025-11-16T14:17:52","guid":{"rendered":"https:\/\/izvestiyakbncran.ru\/?page_id=4934"},"modified":"2026-04-13T08:11:21","modified_gmt":"2026-04-13T07:11:21","slug":"27-5-10-en","status":"publish","type":"page","link":"https:\/\/izvestiyakbncran.ru\/index.php\/en\/27-5-10-en\/","title":{"rendered":"27.5.10 En"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-lora-font-family\" style=\"font-size:24px\"><strong>Bioengineered brain-computer interfaces: an introductory overview of technologies, clinical applications and ethical-legal challenges<\/strong><\/h1>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-9017f2587a38975f1e76bb49ba53d14d\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0\"><strong>A.U. Zammoev, R.N. Abutalipov<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" style=\"margin-top:var(--wp--preset--spacing--20);margin-bottom:var(--wp--preset--spacing--20)\"\/>\n\n\n\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-24a27e19 wp-block-group-is-layout-flex\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0\">\n<p class=\"has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-fa99f84d8051eb763ab85c3007cdb1c2\" style=\"color:#5b1919;text-decoration:underline\"><strong><strong>Upload the full text<\/strong><\/strong><\/p>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-9151b400 wp-block-group-is-layout-flex\" style=\"min-height:0px;margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0\">\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-15bf754d wp-block-buttons-is-layout-flex\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-100 is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-background-background-color has-text-color has-background has-link-color has-border-color has-small-font-size has-custom-font-size wp-element-button\" href=\"http:\/\/izvestiyakbncran.ru\/wp-content\/uploads\/2025\/11\/zammoev-abutalipov-10.pdf\" style=\"border-color:#5b1919;border-style:solid;border-width:2px;border-radius:8px;color:#5b1919;padding-top:0.4rem;padding-right:var(--wp--preset--spacing--40);padding-bottom:0.4rem;padding-left:var(--wp--preset--spacing--40)\">PDF<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:0px;width:0px\" aria-hidden=\"true\" class=\"wp-block-spacer wp-container-content-273e683f\"><\/div>\n<\/div>\n<\/div>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-1c9a0e89c52e463dc1338abac3b1f36b\" style=\"line-height:1.4\"><em><strong><strong>Abstract<\/strong><\/strong>: <\/em>Bioengineered brain-computer interfaces (BBCIs) constitute a rapidly evolving interdisciplinary field at the intersection of neuroscience, bioengineering, materials science, and artificial intelligence. This introductory overview provides a concise synthesis of the current state of research across key domains: invasive, minimally invasive, and non-invasive platforms; emerging technologies (biohybrid interfaces, nanowire probes, in vitro neuromuscular models); clinical applications in neurorehabilitation and communication; and ethical-legal challenges \u2013 from neuroprivacy to cognitive rights. Special attention is given to regional development strategies, including the human-centered approach of the Russian scientific community. The review does not claim to offer a comprehensive analysis but aims to delineate conceptual boundaries and establish an informational foundation for forthcoming  hematic publications focused on in-depth comparative assessments, regulatory modeling, and strategic priorities for clinical translation of BBCIs.<\/p>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-df03325adc83c022634de6b79d43432f\" style=\"line-height:1.4\"><\/p>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-3b4f68308e22c3ebb07f771428e886f3\" style=\"line-height:1.4\"><strong><em><strong>Keywords<\/strong><\/em><\/strong><em>:<\/em> bioengineered brain-computer interfaces (BBCIs), invasive interfaces, neurorehabilitation, biohybrid interfaces, ethical and legal aspects, cognitive rights<\/p>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-df03325adc83c022634de6b79d43432f\" style=\"line-height:1.4\"><\/p>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family wp-elements-cb7a72c4d4c6f3b1321ba03637d9e0af\" style=\"font-size:12px;line-height:1.4\"><strong><strong>For citation<\/strong>.<\/strong> Zammoev A.U., Abutalipov R.N. Bioengineered brain-computer interfaces: an introductory overview of technologies, clinical applications and ethical-legal challenges. <em>News of the Kabardino-Balkarian Scientific Center of RAS<\/em>. 2025. Vol. 27. No. 5. Pp. 125\u2013142. DOI: 10.35330\/1991-6639-2025-27-5-125-142<\/p>\n\n\n\n<p class=\"has-foreground-color has-text-color has-link-color has-lora-font-family wp-elements-17c3333a0b1db39b7fa4a3e1a1572bc4\" style=\"font-size:12px;line-height:1.4\"><\/p>\n\n\n\n<details class=\"wp-block-details has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-8c48c42a14cc7d76695b62523caf268c is-layout-flow wp-container-core-details-is-layout-0ab540ad wp-block-details-is-layout-flow\" style=\"font-style:normal;font-weight:700;line-height:1.5\"><summary><strong>R<\/strong>eferences<\/summary>\n<ol style=\"margin-top:0;margin-bottom:0\" class=\"wp-block-list\">\n<li style=\"font-style:normal;font-weight:400\">Musk E., Neuralink. An integrated brain-machine interface platform with thousands of channels. Journal of medical Internet research. 2019. Vol. 21. No. 10. P. e16194. DOI: 10.2196\/16194<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Goding J.A., Gilmour A., Ulises Alejandro Aregueta Robles, Hasan E. Living bioelectronics: strategies for developing an effective long\u2010term implant with functional neural connections. Advanced Functional Materials. 2018. Vol. 28. No. 12. P. 1702969.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Filipova I.A. Neurotechnologies: development, practical application, and legal regulation. Vestnik of Saint Petersburg University. Law. 2021. Vol. 12. No. 3. Pp. 502\u2013521. DOI:<br>10.21638\/spbu14.2021.302. EDN: GVISZL. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Abutalipov R.N., Zammoev A.U., Nagoev Z.V. Bionanorobotics: conceptualization, perspective and research problems. News of the Kabardino-Balkarian Scientific Center of RAS. No. 6(74). Pp. 11\u201317. EDN: XRUYRN. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Abutalipov R.N., Zammoev A.U., Zagazhezheva O.Z. Interreprezentative network (IRN) and representativeness VR visualization of nanostructures and processes in nano-medium. News of the Kabardino-Balkarian Scientific Center of RAS. 2016. No. 4(72). Pp. 5\u20139. EDN: WKDXXD. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Abutalipov R.N., Zammoev A.U., Anchekov M.I. Perspectives of application of micro and nanosystem equipment in biology and medical diagnostics. Problems and tasks of LoC(Laboratories on the Chip) \/\/ News of the Kabardino-Balkarian Scientific Center of RAS. 2016. No. 6(74). Pp. 5\u201310. EDN: XRUYRD. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Abutalipov R.N., Zammoev A.U. Information service for decision-making support system in the process of designing devices of bionanorobotics. News of the Kabardino-Balkarian Scientific Center of RAS. 2017. No. 6-2(80). Pp. 9\u201312. EDN: YWNDNP. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Zammoev A.U., Abutalipov R.N. Search, research and development of bionanorobotics technologies for the sustainable development of mountain territories in the new techno-economic paradigm. Sustainable Development of Mountainous Regions. 2018. Vol. 10. No. 3(37). Pp. 447\u2013457. DOI: 10.21177\/1998-4502-2018-3-447-457. EDN: YOHKLJ. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Zammoev A.U., Abutalipov R.N. Catalytic self-propelled nanomotors as the basis of the element base for the design of nanomechatronic devices and systems for ionanomachines in bionanorobotics. News of the Kabardino-Balkarian Scientific Center of RAS. 2018. No. 6-2(86). Pp. 149\u2013156. EDN: YZKELR. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Abutalipov R.N., Zammoev A.U. About the possible prospects of the application of magnetotactic bacteria in bionanorobotics. Advanced Systems and Control Problems: Proceedings of the XIV All-Russian Scientific and Practical Conference and X Youth School-Seminar \u201cInformation Control and Processing in Technical Systems\u201d; Southern Federal University. Rostov-on-Don; Taganrog: Southern Federal University Publishing House, 2019. Pp. 200\u2013205. ISBN: 978-5-9275-3146-2. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Zammoev A.U., Abutalipov R.N. Search for methods and study of the possibilities of using modern technologies of virtual prototyping and design of bioengineering systems in the design of bionanodevices and systems of bionanorobotics. News of the Kabardino-Balkarian Scientific Center of RAS. 2020. No. 6(98). Pp. 34\u201342. DOI: 10.35330\/1991-6639-2020-6-98-34-42. EDN: JNLSCR. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Zammoev A.U., Abutalipov R.N. On the possibilities and necessity of applying bioengineering devices and systems of bionanorobotics and biorobotics to address practical medicine challenges. Fundamental Science for Practical Medicine. Additive Technologies, Advanced Materials and Physical Methods in Medicine. Current Issues: Proceedings of the II International Scientific and Practical Conference, Nalchik, September 15\u201318, 2021. Nalchik: Print Tsentr, 2021. Pp. 17\u201318. EDN: OVYATY. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Zammoev A.U., Abutalipov R.N. Soft polymer mechatronic structures for implementing a bio-integrated approach in soft robotics and biorobotics. Advanced Systems and Control Problems: Proceedings of the XVII All-Russian Scientific and Practical Conference and XIII Youth School-Seminar, Dombai, April 4\u20138, 2022. Taganrog: M.R. Maruk Publishing House, Pp. 302\u2013313. EDN: RULOPE. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Abutalipov R.N., Zammoev A.U., Chernyshev G.V. Search for theoretical approaches to the study of cyber-physical systems and environments with intelligent control. News of the<br>Kabardino-Balkarian Scientific Center of RAS. 2024. Vol. 26. No. 6. Pp. 26\u201344. DOI: 10.35330\/1991-6639-2024-26-6-26-44. EDN: CCVAZY. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Hochberg L.R., Serruya M., Friehs G.M., Mukand J.A. Neuronal ensemble control of prosthetic devices by a human with tetraplegia. Nature. 2006. Vol. 442. No. 7099. Pp. 164\u2013171.<br>DOI: 10.1038\/nature04970<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Bj\u00e5nes D.A. et al. Quantifying physical degradation alongside recording and stimulation performance of 980 intracortical microelectrodes chronically implanted in three humans for 956\u20132246 days \/\/ medRxiv. 2024.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Sahasrabuddhe K., Khan A.A., Singh A.P. et al. The Argo: a high channel count recording system for neural recording in vivo. Journal of neural engineering. 2021. Vol. 18. No. 1. P. 015002. DOI: 10.1088\/1741-2552\/abd0ce<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Mitchell P., Lee S.C.M., Yoo P.E. et al. Assessment of safety of a fully implanted endovascular brain-computer interface for severe paralysis in 4 patients: the stent rode with thought-controlled digital switch (SWITCH) study. JAMA neurology. 2023. Vol. 80. No. 3. Pp. 270\u2013278. DOI: 10.1001\/jamaneurol.2022.4847<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Badcock N.A. et al. Validation of the Emotiv EPOC EEG system for research quality auditory event-related potentials in children. PeerJ. 2015. Vol. 3. P. e907.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Ban H.Y. et al. Kernel Flow: a high channel count scalable time-domain functional nearinfrared spectroscopy system. Journal of biomedical optics. 2022. Vol. 27. No. 7. P. 074710.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Mokiienko O.A., Lyukmanov R.Kh., Bobrov P.D. et al. Neurocomputer interfaces based on near-infrared spectroscopy and electroencephalography in post-stroke rehabilitation: a<br>comparative study. Neurology, Neuropsychiatry, Psychosomatics. 2024. Vol. 16. No. 5. Pp. 17\u201323. DOI: 10.14412\/2074-2711-2024-5-17-23. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Pratt E.J. et al. Kernel Flux: a whole-head 432-magnetometer optically-pumped magnetoencephalography (OP-MEG) system for brain activity imaging during natural human experiences. Optical and Quantum Sensing and Precision Metrology. SPIE, 2021. Vol. 11700. Pp. 162\u2013179.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Thwe Y., Maneetham D., Crisnapati P.N. Review of applications in wheelchair control using Emotiv insight and Emotiv Epoc headsets. 2024 6th international conference on cybernetics and intelligent system (ICORIS). IEEE, 2024. Pp. 1\u20136.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Jiang Y., Huang Q., Li Y. Application strategies of brain-computer interface in education from the perspective of innovation diffusion theory. Brain-Apparatus Communication: A Journal of Bacomics. 2024. Vol. 3. No. 1. P. 2376368.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Lupu R.G. et al. BCI and FES based therapy for stroke rehabilitation using VR facilities. Wireless Communications and Mobile Computing. 2018. Vol. 2018. No. 1. P. 4798359.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Zhang A. et al. Nanowire probes could drive high-resolution brain-machine interfaces. Nano Today. 2020. Vol. 31. P. 100821.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Leng Y. et al. Advances in in vitro models of neuromuscular junction: focusing on organ\u2010on\u2010a\u2010chip, organoids, and biohybrid robotics. Advanced Materials. 2023. Vol. 35. No. 41. P. 2211059.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Frank J.A., Antonini M.J., Anikeeva P. Next-generation interfaces for studying neural function. Nature biotechnology. 2019. Vol. 37. No. 9. Pp. 1013\u20131023.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Willett F.R. et al. A high-performance speech neuroprosthesis. Nature. 2023. Vol. 620. No. 7976. Pp. 1031\u20131036.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Willsey M.S. et al. A high-performance brain\u2013computer interface for finger decoding and quadcopter game control in an individual with paralysis. Nature Medicine. 2025. Vol. 31. No. 1. Pp. 96\u2013104.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Cervera M. A. et al. Brain\u2010computer interfaces for post\u2010stroke motor rehabilitation: a meta\u2010analysis. Annals of clinical and translational neurology. 2018. Vol. 5. No. 5. Pp. 651\u2013663.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Ramirez J.G. et al. Intracortical recordings reveal the neuronal selectivity for bodies and body parts in the human visual cortex. Proceedings of the National Academy of Sciences. 2024. Vol. 121. No. 51. P. e2408871121.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Patent No. 2736710 C1 Russian Federation, IPC A61B 5\/0476, A61B 5\/16. System and method for determining fatigue or alertness state based on eeg biometric signal: Application<br>No. 2020107543; filed February 19, 2020; published November 19, 2020 \/ A.N. Makarov, A.A. Makarov, S.M. Goryushko [et al.]; applicant: Limited Liability Company \u201cLaboratoriya<br>Znaniy\u201d (Knowledge Lab LLC). EDN: LFGGRP. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Patent No. 2736711 C1 Russian Federation, IPC A61B 5\/0476, A61B 5\/16. System and method for determining stress state based on EEG biometric signal: Application No. 2020107542; filed February 19, 2020; published November 19, 2020 \/ A.N. Makarov, A.A. Makarov, S.M. Goryushko et al.; applicant: LLC \u201cLaboratoriya Znaniy\u201d (Knowledge Lab LLC). EDN: WBOYEF. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Patent No. 2813807 C1 Russian Federation, IPC A61H 1\/00, A61N 1\/36, A61H 39\/00. Method for multimodal correction of motor and cognitive impairments in patients after ischemic stroke: Application No. 2023105046; filed March 6, 2023; published February 19, 2024 \/ E.V. Kostenko, L.V. Petrova, I.V. Pogonchenkova et al.; applicant: Moscow City State Autonomous Healthcare Institution &#171;Moscow Research and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine of the Moscow Department of Healthcare&#187;. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Patent No. 2844844 C1 Russian Federation, IPC A61H 1\/00, A61N 1\/00. Method for restoring upper limb movements after ischemic stroke using combined electromyostimulation and bimanual robotic mechanotherapy with brain\u2013computer interface technology: filed July 4, 2024; published August 7, 2025 \/ E.V. Kostenko, I.V. Pogonchenkova, L.V. Petrova et al.; applicant: State Autonomous Healthcare Institution of the City of Moscow \u201cS.I. Spasokukotsky Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine of the Moscow Department of Healthcare.\u201d (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Owen A.M., Coleman M.R. Detecting awareness in the vegetative state. Annals of the New York Academy of Sciences. 2008. Vol. 1129. No. 1. Pp. 130\u2013138. DOI: 0.1196\/annals.1417.018<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Monti M.M., Vanhaudenhuyse A., Coleman M.R. et al. Willful modulation of brain activity in disorders of consciousness. New England journal of medicine. 2010. Vol. 362. No. 7. Pp. 579\u2013589. DOI: 10.1056\/NEJMoa0905370<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Yuste R., Goering S., Arcas B.A.Y. et al. Four ethical priorities for neurotechnologies and AI. Nature. 2017. Vol. 551. No. 7679. Pp. 159\u2013163. DOI: 10.1038\/551159a<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Ienca M., Andorno R. Towards new human rights in the age of neuroscience and neurotechnology. Life sciences, society and policy. 2017. Vol. 13. No. 1. P. 5. DOI: 10.1186\/s40504-017-0050-1<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Oxley T.J., Deo D.R., Cernera S. et al. The \u2018Brussels 4\u2019: essential requirements for implantable brain\u2013computer interface user autonomy. Journal of Neural Engineering. 2025. Vol. 22. No. 1. P. 013002. DOI: 10.1088\/1741-2552\/ada0e6<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Oxley T.J., Opie N.L., John S.E. et al. Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity. Nature Biotechnology. 2016. Vol. 34. No. 3. Pp. 320\u2013327. DOI: 10.1038\/nbt.3428<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Oxley T.J. A 10-year journey towards clinical translation of an implantable endovascular BCI. J Neural Eng. 2025. Vol. 22. P. 013001. DOI: 10.1088\/1741-2552\/ad9633<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Ienca M., Valle G., Raspopovic S. Clinical trials for implantable neural prostheses: understanding the ethical and technical requirements. The Lancet Digital Health. 2025. Vol. 7. No. 3. P. e216-e224. DOI: 10.1016\/S2589-7500(24)00222-X<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Lavazza A., Balconi M., Marcello Ienca, Minerva F. Neuralink\u2019s brain-computer interfaces: medical innovations and ethical challenges. Frontiers in Human Dynamics. 2025. Vol. 7. P. 1553905. DOI: 10.3389\/fhumd.2025.1553905<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Ligthart S., Marcello Ienca, Meynen G. et al. Minding rights: Mapping ethical and legal foundations of \u2018neurorights\u2019. Cambridge Quarterly of Healthcare Ethics. 2023. Vol. 32. No. 4. Pp. 461\u2013481. DOI: 10.1017\/S0963180123000245<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Alkhouri K.I. Neuralink\u2019s Brain-computer interfaces and the reshaping of religiouspsychological experience. Conatus-Journal of Philosophy. 2025. Vol. 10. No. 1. Pp. 9\u201356. DOI: 10.12681\/cjp.38734<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Chen X., Wang F., Kooijmans R. et al. Chronic stability of a neuroprosthesis comprising multiple adjacent Utah arrays in monkeys. Journal of Neural Engineering. 2023. Vol. 20. No. 3. P. 036039. DOI: 10.1088\/1741-2552\/ace07e<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Rapoport B.I., Kedzierski J.T., Sarpeshkar R.A glucose fuel cell for implantable brain\u2013machine interfaces. PloS one. 2012. Vol. 7. No. 6. P. e38436. DOI: 10.1371\/journal.pone.0038436<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Karpowicz B.M., Ali Ya.H., Wimalasena L.N. et al. Stabilizing brain-computer interfaces hrough alignment of latent dynamics. Nature Communications. 2025. Vol. 16. No. 1. P. 4662. DOI: 10.1038\/s41467-025-59652-y<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Pun T.K., Khoshnevis M., Hosman T. et al. Measuring instability in chronic human intracortical neural recordings towards stable, long-term brain-computer interfaces. Communications Biology. 2024. Vol. 7. No. 1. P. 1363. DOI: 10.1038\/s42003-024-06784-4<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">DARPA. Next-generation nonsurgical neurotechnology (n3) program: broad agency announcement (baa) HR001118S0067. Arlington, VA: Defense Advanced Research Projects Agency, 2018. 42 p.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Karpov O.E., Andrikov D.A., Maksimenko V.A., Khramov A.E. Transparent artificial intelligence for medicine. Medical Doctor and IT. 2022. No. 2. Pp. 4\u201311. DOI: 10.25881\/18110193_2022_2_4. EDN: DTCAWX. (In Russian)<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\">Ageev A.I., Loginov E.L., Shkuta A.A. Neurocontrol: Convergent integration of the human brain and artificial intelligence. Economic Strategies. 2020. Vol. 22. No. 6(172). Pp. 46\u201357. DOI: 10.33917\/es-6.172.2020.46-57. EDN: XGPRFE. (In Russian)<\/li>\n<\/ol>\n<\/details>\n\n\n\n<details class=\"wp-block-details has-foreground-color has-text-color has-link-color has-lora-font-family has-extra-small-font-size wp-elements-4b1b090eda690b7d7d5b4757f546861c is-layout-flow wp-container-core-details-is-layout-5dafc681 wp-block-details-is-layout-flow\" style=\"font-style:normal;font-weight:700;line-height:1.5\"><summary><strong>Information about the author<\/strong>s<\/summary>\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-b291ae12 wp-block-group-is-layout-flex\" style=\"min-height:0px;margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--40)\">\n<p style=\"font-style:normal;font-weight:400\">A<strong>slan U. Zammoev<\/strong>, Candidate of Technical Sciences, Head of the Scientific-Innovation Center \u201cBiomedical Engineering\u201d of Kabardino-Balkarian Scientific Center of the Russian Academy of Sciences;<br>2 Balkarov street, Nalchik, 360010, Russia;<br>zammoev@mail.ru, ORCID: https:\/\/orcid.org\/0000-0002-7966-3557, SPIN-code: 6317-3115<br><strong>Renat N. Abutalipov<\/strong>, Candidate of Technical Sciences, Senior Researcher of the laboratory \u201cBionanorobotics and Neuroengineering\u201d of the Scientific-Innovation Center \u201cBiomedical engineering\u201d of Kabardino-Balkarian Scientific Center of the Russian Academy of Sciences;<br>2 Balkarov street, Nalchik, 360010, Russia;<br>bnt_nat_2016@mail.ru, ORCID: https:\/\/orcid.org\/0000-0002-0187-563X, SPIN-code: 6219-9432<\/p>\n\n\n\n<p style=\"font-style:normal;font-weight:400\"><\/p>\n\n\n\n<p style=\"font-style:normal;font-weight:400\"><\/p>\n<\/div>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>Bioengineered brain-computer interfaces: an introductory overview of technologies, clinical applications and ethical-legal challenges A.U. Zammoev, R.N. Abutalipov Upload the full text Abstract: Bioengineered brain-computer interfaces (BBCIs) constitute a rapidly evolving interdisciplinary field at the intersection of neuroscience, bioengineering, materials science, and artificial intelligence. 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